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Image Search Results
Journal: medRxiv
Article Title: Multiplexed, quantitative serological profiling of COVID-19 from a drop of blood by a point-of-care test
doi: 10.1101/2020.11.05.20226654
Figure Lengend Snippet: (a) Dose-response curve for recombinant IP-10 spiked into FBS. Each data point represents the average (n = 3) and error bars represent the SEM. The limit-of-detection (LOD) for IP-10 is 0.12 ng/mL. (b) Dose-response curve for anti-SARS-CoV-2 antibodies spiked into FBS. The highest concentration is 10 μg/mL of anti-S1/RBD and 10 μg/mL of anti-N antibodies. (c) Correlation between DA-D4 readout for IP-10 with an ELISA assay performed separately. Samples with a letter designate samples from one individual at different time points, where b occurs later in disease than a. All samples were tested in duplicate on the DA-D4 (with SD shown) except 2b (due to insufficient volume). (d) Antibody reactivity against S1, RBD, and N for sample tested in part c (with SD shown). NC = negative control pooled healthy plasma.
Article Snippet: Simulated doses were prepared using
Techniques: Recombinant, Concentration Assay, Enzyme-linked Immunosorbent Assay, Negative Control
Journal: Virology
Article Title: Emergence of SARS-CoV-2 serotype(s): Is it a matter of time?
doi: 10.1016/j.virol.2023.04.014
Figure Lengend Snippet: Three-dimensional structural representation of the Spike protein of SARS-CoV-2 Omicron. The red spheres represent the S protein mutations in the Omicron BA.1 to BA.5 lineages (details in ). The main targets of neutralizing antibodies are highlighted: N-terminal domain (NTD), fusion peptide (FP), receptor-binding domain (RBD) and receptor-binding motif (RBM). Changes in underpinning subdomain (SD) and heptad repeat 1 (HR-1) are also located in the figure, although their regions have not been indicated. The 3D spike protein image was generated with Visual Molecular Dynamics (VMD) v.1.9.3 ( http://www.ks.uiuc.edu/Research/vmd/ ). The figure also lists key points to consider when discussing whether Omicron may represent a distinct SARS-CoV-2 serotype.
Article Snippet: The
Techniques: Binding Assay, Generated